People sit in my chair and ask me the same question in a dozen different ways. Do I need to start injecting? My answer hasn't changed in twenty years: for most people, no. Your face has over forty muscles and they are supposed to move. What ages skin visibly isn't movement — it's the slow loss of the things that keep skin plump, firm and even. And those can be fed.
That is why Regeneration Booster is the product I reach for when someone wants serious, visible change without a needle anywhere near them.
What's in it, and why that matters
Most "anti-ageing" creams do one job. Regeneration Booster is a patented formulation that does several at once:
- Growth factors — TGF-β1, keratinocyte growth factor and epidermal growth factor, the messengers skin uses to tell itself to renew.
- Four peptides — small chains of amino acids that support the look of firmness and smoothness.
- Cycloastragenol — a purified extract of the astragalus plant and a strong antioxidant.
- The support crew — coenzyme Q10, green tea extract, hyaluronic acid, ceramides and essential fatty acids for hydration and barrier comfort.
It is a light lotion. It goes on after cleansing, morning and night, and it plays well with everything else in a routine — or on its own, which is exactly how it was tested.
What the study found
I am wary of skincare numbers, so here is the study as it was run. Dermatologist Robert Weiss MD put 20 people aged 35 to 75 with moderate photo-ageing on Regeneration Booster alone for 90 days — just a gentle cleanser, the Booster and a broad-spectrum sunscreen. Nothing else. They rated their own skin at baseline and at two weeks, one, two and three months. Eighteen finished. The results were published in the Journal of Drugs in Dermatology (September 2014).
What the participants reported:
- Every one of them saw improvement in at least three of the eight things measured — fine lines and wrinkles, texture, pore size, elasticity, clarity and evenness, redness, hydration and overall skin quality. The average was 6.7 of 8.
- Improvement was significant in all categories except redness by week two, and in every category by day 90.
- Not one case of sensitivity, stinging or irritation. Every participant rated the feel, smell and ease of use positively.
It is a self-assessment study with eighteen people, and I'll say that out loud. But eighteen people using one product and nothing else, with zero reactions and visible improvement in texture and lines around the eyes and cheeks in the clinical photographs, is a better evidence base than almost anything in a department-store beauty hall.
Who it's for
If you are seeing the first fine lines, loss of bounce, a dullness that moisturiser alone doesn't fix — this is the one. If you are retinol-sensitive, or your skin reacts to acids, it is the rare active you can start on day one with no settling-in period. And if you already use retinol, it sits beautifully alongside it: Regeneration Booster in the morning, Retinol Plus at night.
How I'd use it
- Cleanse properly — you know my views on cleansing.
- One pump of Regeneration Booster, pressed into damp skin, face and neck. Morning and night.
- In the morning, follow with a broad-spectrum sunscreen. Every study worth reading pairs its actives with sun protection, and so should you.
- Give it the full three months before you judge it. The study saw change at two weeks; the photographs are at four.
Where to start
- The bottle on its own: Regeneration Booster 30mL.
- The full Marini approach to ageing skin, in one place: our Ageing collection.
- For a gift, or for yourself: the limited Ultimate Christmas Pack puts Regeneration Booster, Marini Reboot PDRN Serum and Retinol Plus together in a Marini makeup bag.
- Not sure which? Book a complimentary skin consultation at the studio in Toorak — fifteen minutes, no charge, and I'll look at your skin, not a quiz.
Skin that moves with you.
Individual results vary. Regeneration Booster is a cosmetic product; study findings describe participants' self-assessed appearance of their skin.